Respiratii alternative - plamanii optionali
Posted: Tue Nov 09, 2021 8:41 pm
"In a study published today (May 14) in Med, researchers present an alternative oxygenation route: through the anus. They introduced oxygen in either gas or liquid form to the intestines of both mice and pigs that had experienced asphyxia or low-oxygen conditions and showed that the animals survived much longer than did those without the treatment."
https://www.the-scientist.com/news-opin ... athe-68769
(Mai tineti minte bancul cu extractia de molar?)
Inca unul (stiati ca hidrogenul sulfurat induce suspended animation? eu nu...)
"Ichinose and his colleagues attempted to extend the period of H2S-induced suspended animation in mice by continuously topping up the supply of the gas in the brain. But what happened surprised the researchers. “We thought that repeating hydrogen sulfide inhalation might prolong suspended animation in mice, so we tested that,” Ichinose says. “And we quickly found out that was not the case. The mice quickly developed tolerance.” Indeed, the mice were able to maintain normal metabolic activity, and the gas no longer induced suspended animation to the extent seen during earlier exposures.
[...] After some trial and error, they discovered that levels of an enzyme called sulfide:quinone oxidoreductase (SQOR), which is normally only found in very low concentrations in brain cells, were increasing in the mouse brains. The buildup occurred as the animals developed a tolerance to H2S, and rose to well beyond typical levels."
"Still, it’s not feasible to inject SQOR into the human brain under conditions of oxygen deprivation, Ichinose notes in an email. A clinical extension of the research, therefore, is to find a drug that could possibly mimic the effects of this enzyme."
(Daca nu nota clar ca nu e fezabil, cine stie, poate cititorii se gandeau ca o fi.)
https://www.the-scientist.com/notebook/ ... oxia-69211
In ansamblu, daca aplicarea metodei 1 cauzeaza suflat de... nas cu productie de H2S ca rezultat, se poate aplica preventiv metoda 2 cu SQOR-ul.
https://www.the-scientist.com/news-opin ... athe-68769
(Mai tineti minte bancul cu extractia de molar?)
Inca unul (stiati ca hidrogenul sulfurat induce suspended animation? eu nu...)
"Ichinose and his colleagues attempted to extend the period of H2S-induced suspended animation in mice by continuously topping up the supply of the gas in the brain. But what happened surprised the researchers. “We thought that repeating hydrogen sulfide inhalation might prolong suspended animation in mice, so we tested that,” Ichinose says. “And we quickly found out that was not the case. The mice quickly developed tolerance.” Indeed, the mice were able to maintain normal metabolic activity, and the gas no longer induced suspended animation to the extent seen during earlier exposures.
[...] After some trial and error, they discovered that levels of an enzyme called sulfide:quinone oxidoreductase (SQOR), which is normally only found in very low concentrations in brain cells, were increasing in the mouse brains. The buildup occurred as the animals developed a tolerance to H2S, and rose to well beyond typical levels."
"Still, it’s not feasible to inject SQOR into the human brain under conditions of oxygen deprivation, Ichinose notes in an email. A clinical extension of the research, therefore, is to find a drug that could possibly mimic the effects of this enzyme."
(Daca nu nota clar ca nu e fezabil, cine stie, poate cititorii se gandeau ca o fi.)
https://www.the-scientist.com/notebook/ ... oxia-69211
In ansamblu, daca aplicarea metodei 1 cauzeaza suflat de... nas cu productie de H2S ca rezultat, se poate aplica preventiv metoda 2 cu SQOR-ul.
